PyTDC (Therapeutics Data Commons)

Use the official PyTDC distribution (import tdc) to discover therapeutic ML tasks, load approved datasets, apply task-appropriate splits, evaluate predictions, and work with curated benchmark groups. Prefer package metadata over copied dataset lists, and plan network/storage effects before constructing any loader.

Verified snapshot

• Research date: 2026-07-23
• PyPI stable: PyTDC 1.1.15, released 2025-03-31
• Package/source repository: mims-harvard/TDC
• Code license: MIT
• PyPI supplies only a source distribution and declares no Requires-Python
• The dependency graph makes CPython 3.11 the reproducible target used here: cellxgene-census==1.15.0 excludes Python 3.12, and PyTDC's constrained RDKit release has no CPython 3.13 wheel
• PyTDC imports deprecated pkg_resources at runtime. Setuptools 82 removed that module; pin the verified compatibility release setuptools 80.9.0.
• tdc.readthedocs.io still identifies itself as TDC 0.4.1; use it as API cross-reference, not as release-version evidence
• Upstream publishes no GitHub tags/releases or maintained changelog. Treat undocumented migration claims as u…