NCATS ARAX

Use ARAX as a constrained knowledge-graph lookup service. Submit reviewed CURIEs and explicit Biolink types, preserve the exact TRAPI exchange, inspect query-edge bindings and provenance, and treat every returned path as a candidate for subsequent verification.

Read query-contract.md before constructing a query. Read output-schema.md when interpreting saved artifacts, warnings, provenance, or partial results.

Safety boundary

• Use only public, nonsensitive research questions. ARAX status facilities may expose query and caller metadata even when store=false is requested.
• Do not submit patient information, confidential research questions, unpublished compound programs, or proprietary target hypotheses.
• Do not present a returned path as a validated mechanism or clinical recommendation.
• Report a zero as "not returned under these constraints," never as evidence that no relationship exists.
• Describe position as unscored response order, never rank.
• Verify important candidates with literature and authoritative databases separately.

Workflow

1. Normalize free text separately, then revie…