HypoGeniC
Scope and scientific boundary
This skill covers the ChicagoHAI software repository
ChicagoHAI/hypothesis-generation and PyPI package hypogenic.
HypoGeniC iteratively proposes and scores textual patterns from labeled data;
HypoRefine adds literature-derived information; union workflows combine banks.
Keep these boundaries explicit:
- The output is a bank of candidate textual hypotheses and task-prediction statistics. It is not experimental confirmation, causal evidence, a clinical conclusion, or proof of scientific novelty.
- Predictive accuracy on held-out examples assesses task utility, not truth of a mechanism. Independent scientific validation still needs domain review, suitable controls, preregistered tests where appropriate, and new evidence.
- For researcher-led formulation of mechanisms and falsifiable predictions,
use
../hypothesis-generation/SKILL.md. For open-ended ideation, use the scientific brainstorming skill.
Default workflow: local review first
Never start a model call automatically.
- Classify the request: HypoGeniC software use, general hypothesis formulation, or downstream scientific validation.
- Record the exa…
